SubtiBank SubtiBank
Version comparison:

2017-04-24 15:34:122025-05-13 04:19:17

description

cell division protein, membrane anchor for FtsZ

cell division protein, membrane anchor for [[protein|FtsZ]]

locus

BSU15280

BSU_15280

geneLength

1320

1323

product

cell division protein

[SW|cell division] protein, member of the [SW|divisome]

essential

yes

no

ec

outlinks

bsu

BSU15280

BSU_15280

Gene

Coordinates

1,596,474 → 1,597,796

1,596,474 1,597,796

Gene

Phenotypes of a mutant

essential [Pubmed|28189581]

cells become elongated [Pubmed|24218584]

the ''[[gene|ftsA]]'' mutation is synthetically lethal with a ''[[gene|sepF]]'' mutation [Pubmed|24218584]

cells become elongated [Pubmed|24218584]

the ''[[gene|ftsA]]'' mutation is synthetically lethal with a ''[[gene|sepF]]'' mutation [Pubmed|24218584]

The protein

Protein family

ftsA/mreB family (according to Swiss-Prot)

[SW|FtsA/MreB family] (according to UniProt)

The protein

[SW|Localization]

septal at the cell membrane [Pubmed|20566861]

septal localization depends on the proton motive force [Pubmed|20566861]

septal at the cell membrane (35% of the molecules) [Pubmed|29439991,20566861]

cytoplasma (65% of the molecules) [pubmed|29439991]

septal localization depends on the proton motive force [Pubmed|20566861]

References

Reviews

19680248

19680248, 28254403

References

Original Publications

16796675, 12081956, 16159787, 11298280, 18776011, 9287012, 1569582, 10878122, 7592498, 20566861, 23036588, 23701187, 24218584, 24224907, 24316672, 28189581

29439991, 16796675, 12081956, 16159787, 11298280, 18776011, 9287012, 1569582, 10878122, 7592498, 20566861, 23036588, 23701187, 24218584, 24224907, 24316672, 28189581, 24746687

The protein

Catalyzed reaction/ biological activity

required for septum recruitment of [[protein|SftA]] [pubmed|29439991]

The protein

Paralogous protein(s)

[[this]]

The protein

Structure

[PDB|3WQT] (from Staphylococcus aureus, 31% identity) [pubmed|24746687]